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Remit and terms of reference

The remit of the CSG and its members is to:

  • Be responsible for developing and overseeing a comprehensive portfolio/strategy for clinical trials and related studies covering the spectrum of major disease areas in musculoskeletal pain
  • Propose and support the development of protocols for trials and related studies. These protocols where relevant will include the design of pilot and feasibility studies to provide proof of concept for definitive studies in terms of recruitment, data collection etc. The CSG will proactively advertise submissions of protocols needed to satisfy these goals, to be done in collaboration with the CSG
  • Review trial and related study protocols proposed by others (including industry proposals), to advise the CLRN and Arthritis Research UK how they may fit into the CSG portfolio/strategy and how the protocol could be assisted in its development
  • Provide robust scientific evaluation, expert advice and support to investigators
  • Ensure consumer involvement in all activities 
  • Work in close collaboration with other CLRN and Arthritis Research 
  • Consider research “add-ons” to established protocols (e.g. pharmacogenetics and qualitative studies)
  • Provide regular reports to the CLRN and Arthritis Research UK of its work and recommendations 
  • Support the development of partnerships with other research funders (e.g. NIHR, MRC, Welcome, other AMRC funders) and industry in developing a comprehensive research programme in musculoskeletal pain 
  • Uphold the highest standards of Research Governance and Good Clinical Practice (GCP) throughout its portfolio according to ICH-GCP guidelines, EU Directives on Clinical Trials and GCP, and UK law 



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