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Highlight notice on innovative and original research projects

Published on 27 August 2015

Along with our focus on pain and fatigue, we are also challenging researchers to submit truly innovative and highly original research projects with the potential to transform how musculoskeletal disease pathogenesis and treatment are viewed. We have played a significant role in supporting pioneering and fundamental research across the spectrum of musculoskeletal disorders. We’re particularly proud of the research we’ve supported that has revolutionised the treatment of rheumatoid arthritis and the significant gains we’ve made in supporting similar research in conditions such as osteoarthritis and rare musculoskeletal diseases. We are committed to continuing this role and seeking to make new discoveries that will lead to the development of new treatments and cures for arthritis in all its forms.

In order to achieve this goal we want to see exciting research focusing on:

  • Resetting the checkpoints in immune tolerance and reversing autoimmunity
  • Discovering the underlying disease mechanisms and processes
  • Identifying truly novel treatment targets
  • Realising the potential for precision medicine

We would encourage collaborative, inter and multi-disciplinary studies and particularly welcome applications which cross disease areas. We recommend cross reference should be made to the criteria for our clinical studies funding scheme which supports interventional testing studies. If there is any ambiguity regarding the correct route for your application please discuss this with the office in the first instance.

The term ‘arthritis’ in this notice is used in its broadest sense and we would encourage applications covering the full spectrum of related inflammatory and musculoskeletal conditions.

Applications should be submitted through our project grant scheme and will be assessed for excellence through the usual rigorous peer review and committee processes, being assessed by our Research Sub-Committee (RSC) and USER stakeholder committee. Lay review forms an important part of the decision making process and applicants are advised to carefully consider the involvement of stakeholders when preparing applications.

Applications will be assessed on:

  • Relevance to this highlight notice
  • Novelty, feasibility and approach taken
  • Potential for long term impact on people with arthritis

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Arthritis Research UK fund research into the cause, treatment and cure of arthritis. You can support Arthritis Research UK by volunteering, donating or visiting our shops.