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Arthritis Research UK Centre for Adolescent Rheumatology

Award Details

  • Principal Investigator
    Professor Lucy Wedderburn
  • Type of grant
    Centre of Excellence Full
  • Amount Awarded
  • Institute
    University College London
  • Location
  • Status
  • Start Date
  • Grant reference number
  • Condition
    Myositis, Systemic lupus erythematosis, Juvenile idiopathic arthritis

This award is jointly funded with Great Ormond Street Hospital Children’s Charity (GOSHCC). Arthritis Research UK is contributing £1,863,790.81 and GOSHCC £250,000 - with extra support from the host institutes.

What are the aims of this research?

The Arthritis Research UK Centre for Adolescent Rheumatology aims to improve the health and wellbeing of adolescents, with arthritis and other rheumatic conditions, by undertaking cutting edge research and ensuring that adolescent patients can be part of research and clinical trials. The centre originally launched in 2012 and has been renewed for a further 5 years. In partnership with young people, the centre has defined specific goals for the next 5 years to drive forward research in four key areas, and build on the work already achieved by the centre:

  1. Enhance understanding of the science of adolescent-related arthritis, to develop better treatments and improve clinical care
  2. Contribute to understanding of the adolescent immune system in relation to inflammatory diseases such as arthritis and lupus
  3. Improve health care provision and enable self-management in young people with arthritis
  4. Support continued growth of the Barbara Ansell National Network for Adolescent Rheumatology (BANNAR), a network of interested and committed professionals working in adolescent and young adult rheumatology in the UK.

Why is this research important?

Having arthritis during adolescence is not easy and it is vital that teenagers with healthcare problems are given the best treatment to address their needs. The centre aims to bring together experts from different fields, including; immunology, hormone biology, psychology, pain and computer science, and enabled establishment of a National Network, all working towards the common goal to support adolescents with arthritis and other rheumatic conditions. In parallel, the centre will secure the next generation of researchers in this growing area, to ensure sustainability of the centre, while enhancing patient involvement at every level of centre research activity. So far, patient involvement has driven the centre’s research agenda, informing them on research priorities and study design, facilitated recruitment of research participants and informed dissemination strategies about adolescent arthritis and related conditions.

How will the findings benefit patients?

Understanding how and why arthritis develops and progresses in this age group should lead to the discovery of new or better treatments as well as methods to prevent complications that adolescents with arthritis develop in later life (such as heart disease) and tests that may predict how the disease will progress. The centre will integrate excellent care with excellent research as teenagers travel through the journey from paediatric (child) to adult care helping to provide better long-term outcome for these patients. The centre will also help raise awareness of the health needs of adolescents with rheumatic disease and ensure that teenagers have uninterrupted and full access to clinical trials, giving them access to the latest treatments.

For more information on the centre, visit the centre's website. Additionally, for further information on BANNAR, please visit their website.

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