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Causes of musculoskeletal pain

Back to Widespread musculoskeletal pain

Determining whether a new presentation of musculoskeletal pain is a sign of a significant underlying rheumatological condition isn't always straightforward.

Signs and symptoms can be subtle. Coexisting musculoskeletal conditions, especially osteoarthritis, can complicate the process of diagnosis.

Potential causes of widespread or diffuse musculoskeletal pain include:

  • viral or bacterial infection-related arthritis
  • crystal-related arthropathies
  • systemic rheumatic disease
  • spondyloarthropathies
  • thyroid disorders
  • malignancy
  • metabolic bone disorders
  • osteoarthritis
  • fibromyalgia
  • hypermobility syndromes.
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