Will NSAIDs affect fertility, pregnancy or breastfeeding?
If you’re planning a family or you become pregnant you should discuss your medications with your doctor as soon as possible.
There’s mixed evidence concerning a small increased risk of miscarriage if NSAIDs are taken around the time of conception. You may therefore wish to avoid NSAIDs in the first three months of pregnancy especially if you’ve previously had difficulty becoming pregnant.
NSAIDs other than low-dose aspirin should be stopped at 32 weeks to prevent premature closure of the baby’s ductus arteriosus (a blood vessel which normally closes soon after the birth). Low-dose aspirin (up to 75 mg) may be continued throughout pregnancy and is recommended if the mother has high blood pressure.
There is little evidence relating specifically to the use of COX-2 NSAIDs (coxibs) during pregnancy so it’s recommended that these are avoided.
NSAIDs do pass into the breastmilk but there’s no evidence that this is harmful to the baby.
It’s not thought that NSAIDs are likely to be harmful if taken by men wishing to father a child.