What is methotrexate and why is it prescribed?
Methotrexate is a type of drug known as a disease-modifying anti-rheumatic drug (DMARD). It's prescribed for rheumatoid arthritis, psoriatic arthritis and vasculitis. Read more
How do I take methotrexate and how long does it take to work?
Methotrexate is usually taken in tablet form once a week on the same day. The tablets should be swallowed whole and not crushed or chewed. Alternatively, methotrexate may be given once a week by injection, usually subcutaneous, if there are side-effects with tablets. It's a long-term treatment, so it may be 3–12 weeks before you start to notice the benefits. Read more
What are the possible risks and side-effects of methotrexate?
Side-effects of methotrexate can include nausea, vomiting and diarrhoea. It can also affect your blood count and make you more likely to develop infections. Read more
Can methotrexate affect other medications and treatments?
Methotrexate may be prescribed along with other drugs to treat your condition. Some drugs however, can interact with methotrexate. Check with your doctor before starting any new medications, and mention you’re on methotrexate if you’re treated by anyone other than your usual rheumatology team. Read more
Can I drink alcohol if I'm on methotrexate?
If you're on methotrexate, you should only drink alcohol in small amounts because methotrexate and alcohol can interact and affect your liver. Read more
Can methotrexate affect fertility, pregnancy or breastfeeding?
Current guidelines state that methotrexate may harm the baby if taken during pregnancy. If you're on methotrexate and you want to start a family or you become pregnant, talk to your doctor as soon as possible. Read more