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What are the symptoms of calcium crystal diseases?

The two most common types of calcium crystal disease, acute CPP crystal arthritis (pseudogout), and acute calcific tendinitis (acute periarthritis), have different symptoms.

Symptoms of acute CPP crystal arthritis include:

  • sudden pain and stiffness in affected joint (most commonly the knee)
  • swelling and tenderness
  • red, inflamed skin over the joint
  • raised temperature
  • generally feeling unwell

These symptoms tend to last several days to 2 weeks before completely settling.

Symptoms of acute calcific tendinitis include:

  • painful swelling around the joint (most commonly in the shoulder)
  • bulging tendons due to crystal deposits
  • redness and tenderness around the joint

These symptoms usually settle back to normal after 2–4 weeks.


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