Anthocyanidins are nutritional supplements. They have strong antioxidant properties that can, in theory, support and prevent the destruction of collagen in muscles.
The effectiveness of anthocyanidins for fibromyalgia was only tested in one small RCT. No reduction in pain and an unconfirmed improvement in fatigue and sleeping problems were found. Because the data is limited, we can’t yet give a reliable evaluation of the role of this treatment for fibromyalgia.
What are they?
Family: Nutritional supplement
Scientific name: Anthocyanidins
Other names: Colladeen®
Anthocyanidins are a subgroup of flavonoids, which are chemicals that are made from the parts of some plants that don’t provide nutrients. You can buy anthocyandins capsules (Colladeen®) over the counter in pharmacies or over the internet.
How do they work?
Several laboratory studies have shown that anthocyanidins can act as strong antioxidants. Anthocyanidins can also prevent the destruction of collagen in the muscles, a problem that has been observed in some people with fibromyalgia.
Are they safe?
Reported side-effects on short-term usage include:
- stomach upsets
- problems passing urine.
There are no reports on the long-term safety of anthocyanidins and interactions with other drugs haven’t been well studied.
Doses ranging from 40–120 mg a day have been used in an RCT. No trials have been conducted to find the best dosage in musculoskeletal conditions.
Anthocyanidins trials for fibromyalgia
A summary of the scientific evidence on anthocyanidins for the treatment of fibromyalgia. Read more
References for the evidence on anthocyanidins. Read more