Centre for genetics and genomics
This centre is based at the University of Manchester. The aim of their research is to understand the role of genetic factors in determining whether particular people are at risk of developing inflammatory arthritis and what happens when they do.
Arthritis is a complex condition for which susceptibility is determined by a combination of genetic and environmental or lifestyle factors. This centre focuses on rheumatoid arthritis, psoriatic arthritis and juvenile idiopathic arthritis.
Researchers at this centre, along with international collaborators, have contributed to large genetic studies which have identified many genetic risk factors associated with these conditions. Researchers at this centre now face the considerable challenge of examining these risk regions in more detail to determine how subtle changes in the genetic code influence the disease process.