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Issue 28 Synovium (Autumn 2009)
Here is another of those 'It makes you think...' papers. An interesting population-based study of ageing in the elderly population of Reykjavik1 has demonstrated that there is a positive and linear relationship between the severity of hand osteoarthritis (scored from photographs) and atherosclerotic disease (scored from the thickness of calcified plaques in the aorta, carotid arteries and coronary arteries) – but only in women! Despite the increased incidence and severity of pathology observed in the women in the study, they did not appear to have an increased incidence of cardiovascular or cerebrovascular events. Hmm?