We are using cookies to give you the best experience on our site. Cookies are files stored in your browser and are used by most websites to help personalise your web experience.

By continuing to use our website without changing the settings, you are agreeing to our use of cookies.

Find out more
For more information, go to

Why don't you have any information on Targinact?

Q) I searched your site for tramadol and saw a quote about there being a big gap in the market since co-proxamol was withdrawn, and that between paracetamol and tramadol there was a need for a stronger painkiller without the constipating side-effects of codeine (in co-codamol) and dihydrocodeine (in co-dydramol). I then searched your site for Targinact (which was featured in the Daily Mail recently) and it returned no result...this I find quite unbelievable and suggest that you immediately rectify. I'm a chronic pain sufferer among the millions abandoned by the medical profession.
Graham Thorpe, Hemel Hempstead, Hertfordshire (Spring 2011)

A) I agree that the withdrawal of co-proxamol has been a big blow to many patients. Funnily enough, small supplies of this drug are still available, if you know where to look for it and if your GP will prescribe it. And I completely agree that the constipating effect of morphine-like drugs is a big drawback. However, I'm not sure that Targinact is the perfect solution. The Drug and Therapeutics Bulletin, a respected independent publication, had this to say about it: 'The studies have provided few data to show that Targinact reduces, let alone eliminates, the need for laxatives in the long term, or whether it offers advantages for people with cancer. There are no published studies comparing Targinact with other oral strong opioids given with regular stool-softening and stimulant laxatives. Targinact is more expensive than oral morphine plus regular laxatives.'


0800 5200 520

Our new helpline: Call us for free information, help and advice on your type of arthritis.

All calls are recorded for training and quality purposes

More Information Close
For more information, go to or call 0300 790 0400 to order the complete printed booklet.
Arthritis Research UK fund research into the cause, treatment and cure of arthritis. You can support Arthritis Research UK by volunteering, donating or visiting our shops.