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Could rituximab affect a perm?

Q) My wife has rheumatoid arthritis and has been treated with rituximab. We would be grateful if there's any information on whether the use of this drug might affect the perming of her hair. She has had three perms since having the treatment – the first was two weeks after the second infusion –and none of them have taken. We therefore wondered if there's a possible link?
W J Lanigan, Bovey Tracey, Devon (Spring 2011)

A) Well this is a new one for me. I have heard of hair loss, although this isn't so much of a problem with rituximab. People taking methotrexate are much more likely to complain of hair thinning. Applying a permanent set to your hair is a chemical-based treatment and as such is fairly harsh on the hair. The slow rate of growth of hair, and the short time after the rituximab, suggests to me that the rituximab had nothing to do with the perm as the drug wouldn't yet have been incorporated into the hair. I must remember to ask my other patients!


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