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> > > > How do I take sulfalsalazine and how long does it take to work?

How do I take sulfalsalazine and how long does it take to work?

Sulfasalazine is generally prescribed as Salazopyrin EN-Tabs. These tablets are specially coated so that they don't dissolve quickly in your stomach. 

Sulfasalazine tablets should be taken with a glass of water and should be swallowed whole, not crushed or chewed.

Your doctor will advise you on the correct dose. Usually you’ll start on a low dose, e.g. one 500 mg tablet daily. This is usually increased gradually over a period of about four weeks – typically to two 500 mg tablets taken twice daily. The dose may be adjusted according to the severity of your symptoms.

How long does sulfasalazine take to work?

Sulfasalazine doesn’t work immediately. It may be at least 12 weeks before you notice the benefit. Because it's a long-term treatment, it's important to keep taking sulfasalazine (unless you have severe side-effects):

  • even if it doesn't seem to be working at first
  • even when your symptoms improve (to help keep the disease under control).


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