Print page Reset all

What is sulfasalazine?

Sulfasalazine is a disease-modifying anti-rheumatic drug (DMARD). It dampens down the underlying disease process, rather than simply treating symptoms.

Why is sulfalsalazine prescribed?

Sulfasalazine is used to treat conditions such as rheumatoid arthritis, psoriatic arthritisreactive arthritis and arthritis associated with bowel inflammation.

How do I take sulfalsalazine and how long does it take to work?

Sulfasalazine is usually taken in tablet form. Each tablet contains 500 mg. You may start on a low dose (e.g. 500 mg once daily) and then increased to a higher dose (e.g. 1 g twice daily). It may be at least 12 weeks before you notice any benefit.

What are the possible side-effects of sulfasalazine?

In some patients sulfasalazine can cause nausea (feeling sick), diarrhoea, stomach pain, dizziness, headache and skin rashes. It can sometimes affect your blood or liver.

What are the risks of sulfasalazine?

There may be some risks in taking sulfasalazine. This section gives important information about these risks, including the effects on:
  • vaccinations
  • drinking alcohol
  • fertility and pregnancy
  • breastfeeding

What else should I know about sulfasalazine?

This section gives answers to some common questions about taking sulfasalazine:
  • Are there any alternatives?
  • Will I need any special checks?
  • Can I take other medicines?

Search arthritis information