Can methotrexate affect fertility, pregnancy or breastfeeding?
Current guidelines state that methotrexate may harm the baby if taken during pregnancy. You can still have a successful pregnancy if you stop taking methotrexate in plenty of time before trying for a baby.
Women using this drug should take contraceptive precautions. After stopping methotrexate you should continue using contraception for at least three months.
You should talk to your doctor as soon as possible if you're planning to start a family. If you become pregnant while taking methotrexate, you should stop taking it and see your doctor as soon as possible.
Previously, there was concern that methotrexate may affect sperm and thus any fertilised egg but it has not been shown to be a problem in research studies. Therefore, current guidelines advise that men do not need to stop taking methotrexate before trying for a baby. You should talk to your rheumatologist about these matters.
The drug may pass into breast milk and the effects upon your baby are uncertain, so you shouldn't breastfeed if you're on methotrexate.