Methotrexate

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What is methotrexate?

Methotrexate is a type of disease-modifying anti-rheumatic drug (DMARD). It's prescribed for rheumatoid arthritis, psoriatic arthritis and vasculitis. Read more >

What are the possible side-effects of methotrexate?

In some patients methotrexate can cause nausea (feeling sick), vomiting, diarrhoea, mouth ulcers, hair loss and skin rashes. It can also make you more likely to develop infections. Read more >

What are the risks of taking methotrexate?

If you’re on methotrexate it’s recommended that you avoid live vaccines and only drink alcohol in small amounts. Methotrexate can affect fertility and is likely to harm the baby if taken during pregnancy or while breastfeeding.

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What else should I know about methotrexate?

Before you start taking methotrexate, your healthcare team will discuss other treatment options with you. You'll have a blood test and may have a chest x-ray and breathing tests.

While taking methotrexate, you'll have regular blood tests. Some drugs interact with methotrexate, so you should discuss any new medications (including complementary medicines) with your doctor before starting them and always tell any other doctor treating you that you’re on methotrexate.

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