For more information, go to www.arthritisresearchuk.org

How do I take leflunomide and how long does it take to work?

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Leflunomide tablets are taken once a day. Swallow the tablets whole without crushing or chewing them. It's best to take them at the same time every day. You can take them with or without food.

Your doctor will advise you about what dose you should take – usually either 10 mg or 20 mg a day.

Leflunomide doesn’t work immediately. It may take six weeks or more for you notice any benefit and several months before you feel the full effect. Because it's a long-term treatment it's best to keep taking leflunomide (unless you have severe side-effects):

  • even if it doesn't seem to be working at first
  • even when your symptoms improve (to help keep your condition under control).


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