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What is febuxostat and why is it prescribed?

Febuxostat reduces the production of uric acid in the body and so reduces the risk of an attack of gout.

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How do I take febuxostat and how long does it take to work?

Febuxostat is given as tablets, which should be taken with water.

The usual starting dose is 80 mg daily, which is increased to 120 mg daily if your urate level isn't reducing sufficiently.

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What are the possible risks and side-effects of febuxostat?

Side-effects of febuxostat are uncommon but can include diarrhoea, headaches, skin rashes and nausea (feeling sick). Febuxostat can sometimes cause abnormal liver test results.

When you start on feboxostat you may have more gout symptoms to begin with, but this doesn't mean the treatment isn't working.

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Can febuxostat affect other medicines and treatments?

You can take other drugs alongside febuxostat. However, some medicines can interact with it, so check with your doctor before starting any new medications.

Febuxostat won't affect any vaccinations you may need.

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Can I drink alcohol while I'm on febuxostat?

There's no significant interaction between alcohol and febuxostat.

However, keeping alcohol consumption within recommended amounts will help to reduce the risk of gout.

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Can febuxostat affect fertility, pregnancy or breastfeeding?

Febuxostat isn't recommended if you're pregnant or breastfeeding as we don't yet know what effects it might have on the baby.

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