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What is cyclophosphamide and why is it prescribed?

In some conditions where the immune system is overactive cyclophosphamide is used to suppress the immune system (by damaging raplidly multiplying cells) to bring the disease under control. Cyclophosphamide doesn't work straight away – it may take six weeks or more before you notice an improvement.

Cyclophosphamide is used to treat several different types of rheumatic disease, including:

Cyclophosphamide is often prescribed along with steroid tablets or steroid injections.

Your doctor will arrange for you to have blood and urine tests before you start treatment, as cyclophosphamide can affect the blood and the bladder. You'll then have regular checks while you're on cyclophosphamide. You should receive full information about the treatment plan before starting cyclophosphamide and you may be asked to sign a consent form.

For more information, go to www.arthritisresearchuk.org.
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