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Can cyclophosphamide affect fertility, pregnancy or breastfeeding?

Cyclophosphamide can reduce fertility in both men and women, though stopping the drug may reverse this effect. You should discuss this with your doctor, preferably before you start the treatment. There may be options available to help you preserve your fertility if this is important to you (for example, sperm storage).

You should not use cyclophosphamide if you're pregnant. Men and women taking cyclophosphamide must take contraceptive precautions, and should continue doing so for at least three months after treatment is stopped. If you're planning a family or if you become pregnant while taking cyclophosphamide, you should discuss this with your doctor as soon as possible.

You shouldn't breastfeed if you're on cyclophosphamide. The drug may pass into the breast milk and could be harmful to your baby.


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