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Certolizumab pegol

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What is certolizumab pegol and why is it prescribed?

Certolizumab pegol is an anti-TNF (anti-tumour necrosis factor) drug. It blocks the action of TNF protein and so reduces inflammation in conditions including rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis.

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How do I take certolizumab pegol and how long does it take to work?

Certolizumab pegol is usually given as a 200 mg injection every 2 weeks. If it works for you, you’ll probably feel better in 2–12 weeks.

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What are the possible risks and side-effects of certolizumab pegol?

The most common side-effects of certolizumab pegol are reactions at the injection site, such as redness, swelling or pain.

It can also make you more likely to develop infections.

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Can certolizumab pegol affect other medicines and treatments?

You can take other drugs alongside certolizumab pegol, but check with your doctor before starting any new medications.

Live vaccines aren't usually recommended, and you may need to stop certolizumab pegol if you're having an operation.

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Can I drink alcohol while I'm on certolizumab pegol?

There's no known interaction between certolizumab pegol and alcohol but, if you're also on methotrexate, you should drink only in moderation.

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Can certolizumab pegol affect fertility, pregnancy or breastfeeding?

Current guidelines state that certolizumab pegol can be used if you're pregnant, and research suggests it doesn't pass into breast milk.

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