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Can azathioprine affect fertility, pregnancy or breastfeeding?

Current guidelines state that azathioprine can be taken during pregnancy at a dose equivalent to 2 mg per kilogram or less of your body weight. It's important that the mother's health is maintained during pregnancy and disease flares are avoided by not stopping azathioprine.

If you're planning a family or become pregnant while taking azathioprine, you should discuss this with your doctor as soon as possible.

Azathioprine may pass into the breast milk. If you're on azathioprine and wish to breastfeed you should discuss this with your rheumatology team beforehand, although current guidelines now state that it is safe to continue in this instance.


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