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Can amitriptyline affect other medicines and treatments?

Can I take other medicines alongside amitriptyline?

Amitriptyline may be prescribed along with other drugs to treat your condition. However, some drugs may interact with it, so check with your doctor before starting any new medications, and remember to mention you're on amitriptyline if you're treated by anyone other than your usual doctor.

  • You may be prescribed painkillers (for example, codeine or tramadol) alongside amitriptyline – this could make you more drowsy.
  • If you're prescribed a combination of an SNRI or SSRI antidepressant and amitriptyline, you may need more careful monitoring, especially if you're also on treatment for blood pressure or heart problems.
  • Don't take over-the-counter preparations or herbal remedies without discussing this first with your healthcare team.

Can I have vaccinations while I'm on amitriptyline?

You can have vaccinations while on amitriptyline.

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