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What is amitriptyline?

Amitriptyline is a tricyclic antidepressant which is used to relieve the chronic (long-term) pain of arthritis and related conditions. It relaxes muscles and improves sleep that’s being disturbed by pain, and it may also help with anxiety or depression resulting from the pain. Read more >

How do I take amitriptyline and how long does it take to work?

Amitriptyline is usually taken as tablets or syrup once a day, about two hours before bedtime. The usual dose for chronic pain is 5–50 mg daily, though higher doses may be prescribed. 

It may take several weeks before it starts to work.

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What are the possible side-effects of amitriptyline?

The most common side-effect of amitriptyline is a dry mouth, but you may also feel drowsy or spaced out during the day. Reducing the dose may help but some people can't tolerate even low doses. Read more >
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