Can allopurinol affect other medicines and treatments?
You'll probably need a non-steroidal anti-inflammatory drug (NSAID), colchicine or steroids to deal with attacks of gout – especially in the early stages of allopurinol treatment. However, some drugs may interact with allopurinol, so you should discuss any new medication with your doctor before starting it, and you should always tell anyone else treating you that you're taking allopurinol.
- Allopurinol interacts with the immunosuppressant drugs azathioprine and mercaptopurine and these drugs should not generally be used with allopurinol.
- Allopurinol may increase the risk of developing a rash with the antibiotics ampicillin and amoxicillin.
- Allopurinol may increase the effect of warfarin and other drugs that thin the blood (anticoagulants), so you may need to have your blood clotting tested more frequently.
Can I have vaccinations while I'm on allopurinol?
You can have vaccinations while on allopurinol.