Vitamins B Complex
Vitamin B complex is a type of non-antioxidant vitamin. We don’t fully understand how this type of vitamin may treat arthritis-related conditions, but evidence from trials suggests that vitamins B3, B9 and B12 might be of some benefit for treating osteoarthritis, particularly in improving joint mobility and hand grip. Vitamin B6 may reduce levels of markers of inflammation in rheumatoid arthritis, but there’s no evidence from trials that it improve clinical measures.
What is it?
Family: Nutritional supplement
Scientific names: Vitamin B3 (niacinamide), vitamin B12 (Cobalamin), vitamin B9 (folic acid)
Vitamins are nutritional substances which you need in small amounts in your diet. Except for vitamin B12, which can be stored in your liver for up to four years, your body stores all water-soluble vitamins for only a brief period of several weeks to several months and then gets rid of them through the urine. This is why you need to take water-soluble vitamins daily.
Vitamins can be found in foods (natural vitamins) or can be produced in laboratories (synthetic vitamins). You can buy vitamin capsules from high-street shops.
How does it work?
Several studies have found that vitamin B12 plays a role in controlling bone metabolism. Another study found that people with osteoarthritis have low intake of vitamin B9 (folic acid).
Is it safe?
We don’t yet know what the best dose of vitamin B complex is for arthritis and related conditions, but RCTs have used daily doses of 3 g of vitamin B3, 6,400 μg of vitamin B9 and 20 μg of vitamin B12. Vitamin B9 (folic acid) supplements are safe, even with high doses. Apart from occasional gastrointestinal symptoms and itching, vitamin B12 has a high safety profile.
No serious drug interactions have been reported with low or medium intake of non-antioxidant vitamins.
Vitamin B complex trials for rheumatoid arthritis
A summary of the scientific evidence on vitamin B complex for the treatment of rheumatoid arthritis. Read more
Vitamin B complex trials for osteoarthritis
A summary of the scientific evidence on vitamin B complex for the treatment of osteoarthritis. Read more
References for the evidence on vitamin B complex. Read more