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Duhuo Jisheng Wan trials for osteoarthritis

In this trial, 200 participants with osteoarthritis of the knee were randomly given daily doses of one of the following:

  • 75 mg diclofenac tablets
  • 9 g Duhuo Jisheng Wan tablets
  • placebo tablets identical to the diclofenac
  • placebo tablets identical to the Duhuo Jisheng Wan.

The groups were compared with respect to side-effects and effectiveness over a four-week period.

  • Compared to the corresponding placebo groups, participants who received either Duhuo Jisheng Wan or diclofenac had significantly lower scores for pain and stiffness.
  • Compared to diclofenac, the beneficial effects of Duhuo Jisheng Wan were slower to develop.
  • Around 30% of participants in both groups receiving diclofenac and Duhuo Jisheng Wan reported side-effects; however, both groups also reported significantly more side-effects than the placebo groups.
For more information, go to www.arthritisresearchuk.org.
Arthritis Research UK fund research into the cause, treatment and cure of arthritis. You can support Arthritis Research UK by volunteering, donating or visiting our shops.